The present invention refers to a process for preparing a compound of formula
(I) or a pharmaceutically acceptable salt thereof:
wherein R is (C:-C r o)alkyl, or co-trifluoro(Cr-Cro)alkyl; N,RU I & Rr and R2 aro, independently, hydrogen, hydroxy, (Cr-Cs)alkoxy, (Cr-Ca) alkylthio, 10 halo, trifluoromethyl
or 2,2,2-trifluoroethyl; or one of Rr and Rz is in ortho position to the R- O-
group and, taken together with the same R-O-, represents a (Cz-Ce)alkyl;
R.< o- o- group where Ro is R: and R+ &re, independently, hydrogen, (Cr-Ca)alkyl;
or Ra is hydrogen and Rs is a group selected from -cHz-oH, -cHz-o-(cr-co)alkyl,
-cH(cH:)-oH, -(cHz)z-S-CH3, benzyl 15 and 4-hydroxybenzyl; or Ra and
Rs, taken together with the adjacent carbon atom, form a (C:- Ce)cycloalkyl
residue; Rs and Ro are independently hydrogen or (cr-co)alkyl; or taken
together with the adjacent nitrogen atom form a 5-6 membered monocyclic
saturated heterocycle, optionally containing one additional heteroatom
chosen among -O-, -S- and -NRz- where Rz is hydrogen 20 or (Cr-Co)
alkyl; R4 R3 and wherein optionally one or more hydrogen atom in the goups R, Rt, Rz, R:, Rr,
Rs and Ro, preferably in the R group, can be substituted by a deuterium
atom.
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